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To date no biomarker analyses of response to
2019-04-25
To date, no biomarker analyses of response to VEGFR targeting agents in breast cancer patients with bone predominant metastatic disease has occurred. Although the bone turnover markers serum c-telopeptide (sCTx), and urinary N-telopeptide (uNTx) were measured at baseline, and uNTX measured every 8 w
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Introduction Pulmonary vein isolation PVI is
2019-04-25
Introduction Pulmonary vein isolation (PVI) is an established strategy of paroxysmal atrial fibrillation (PAF) ablation [1–3]. Radiofrequency catheters have been the standard for AF ablation; however, PVI using balloon-based ablation has been increasingly adopted by electrophysiology laboratories a
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Although Afnan Holmes and colleagues report covers
2019-04-25
Although Afnan-Holmes and colleagues\' report covers substantial ground, several issues remain unexamined. For example, why have facility delivery rates in the country stagnated at roughly 50% over the past decade? Although enhancement of women\'s agency in making health-care decisions is necessary,
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br Signal averaged electrocardiography SAECG
2019-04-24
Signal-averaged electrocardiography (SAECG) SAECG is a high-resolution electrocardiographic technique developed in the 1970s for detecting patients who are prone to SCD after MI. It is based on the theory that lethal ventricular arrhythmias leading to SCD often have a reentrant mechanism. Reentry
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br Study limitations br Conflict of interest br
2019-04-24
Study limitations Conflict of interest Case report Discussion DFT testing is usually recommended to ensure proper functioning of the ICD/CRT-D and verify that there is no acute lead dislodgement [1,2]. For patients with impaired cardiac function, VF induction and shock delivery can cause
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The canonical or catenin dependent Wnt signaling pathway is
2019-04-24
The canonical, or β-catenin dependent, Wnt signaling pathway is critical for the regulation of osteoblast proliferation and survival [95]. Soluble inhibitors of the canonical Wnt pathway such as Dickkopf (DKK1), produced by OBL, and sclerostin, from osteocytes, play important roles in the regulation
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As shown in Fig out of
2019-04-24
As shown in Fig. 2, 40 out of the 60 patients (66.6%) who developed amiodarone-induced hypothyroidism, and 10 out of the 30 patients (33.3%) who developed amiodarone-induced hyperthyroidism, were diagnosed within two years of phosphatidylinositol 4-kinase of amiodarone therapy. Amiodarone-induced h
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br The Medical Education Partnership Initiative
2019-04-24
The Medical Education Partnership Initiative (MEPI) is an innovative and potentially transformative 5-year programme, established by the US Government in 2010, to increase the number of doctors to meet crucial human resource needs in sub-Saharan Africa. MEPI allows African institutions that cgrp a
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Fourth the enormous investment in accessible medicines
2019-04-24
Fourth, the enormous investment in accessible medicines and medical products without investment in checking their quality is profoundly illogical. WHO estimates that only 7% of sub-Saharan countries had a “moderately functioning MRA”. We cannot expect the world\'s medicine supply to improve without
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Esta idea se reforz con
2019-04-24
Esta idea se reforzó con uno de los elementos identitarios oficiales de la organización, su propio escudo. La comil tomó cuatro de las características reconocibles del pgt histórico; es decir, las siglas, la estrella, la hoz y el martillo, y el círculo que enmarcó todos estos símbolos, mismos que de
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El primero corresponde al Frente Guerrillero Edgar
2019-04-24
El primero corresponde al Frente Guerrillero Edgar Ibarra (fgei), grupo perteneciente GDC-0879 manufacturer las Fuerzas Armadas Rebeldes (far) de Guatemala, que inició operaciones en 1962 en la sierra de Zacapa, y que en enero de 1966 fue objeto de un amplio fotorreportaje publicado en la revista me
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br Methods br Results Four patients withdrew from
2019-04-23
Methods Results Four patients withdrew from the study due to elevated liver function, allergy to oxaliplatin, refusal of surgery, and refusal of chemotherapy, respectively. The total number of patients included in the final analysis was 31. The patients’ characteristics are presented in Table
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br In Gretchen Stevens and colleagues update
2019-04-23
In Gretchen Stevens and colleagues\' update of global, regional, and national trends in haemoglobin concentration and levels of anaemia emphasises both the massive extent of the problem, and its very slow rate of improvement. About 30% or more of women and children younger than 5 years are affect
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Varios republicanos espa oles de s lida
2019-04-23
Varios republicanos españoles de sólida posición económica residentes en México habrían recibido esta carta de extorsión, entre ellos personajes como: Fernando Rodríguez Miaja, Máximo Muñoz, Jerónimo Bugeda o Juan Simeón Vidarte, quien se apresuró Madecassoside denunciarlo a las autoridades. Sean ci
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La fotograf a reforz el car cter militarista del pgt
2019-04-23
La fotografía reforzó el carácter militarista del pgt-pc. El ajusticiamiento de Zepeda Martínez perdió su fuerza política al carecer de los mecanismos de propaganda que acompañan una acción de gp120 este tipo. Si bien los recursos gráficos explotados por el periodismo difundieron la muerte del cónsu
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