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In patients who develop bone metastases these are commonly
2019-04-26
In patients who develop bone metastases, these are commonly diagnosed at the time of their initial work up for their metastatic disease (∼80%) [7], although others can develop skeletal metastases at any time during the disease course. The consequences of bone metastases include pain (∼80%) [3,6,8] a
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The lead ECG and dimensional geometrical maps for corrected
2019-04-25
The 12-lead ECG and 2-dimensional geometrical maps for corrected RT interval difference and corrected Tp–e interval difference obtained by using 187-ch RIDM-ECG before and during the intravenous amiodarone infusion for representative cases are shown in Figs. 1 and 2 respectively. The mean value of Q
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El n mero de correspondiente al
2019-04-25
El número 61 de , correspondiente al segundo semestre de 2015, ofrece seis artículos en su sección Política y Sociedad. El primero congo red cargo de Wilfredo Padrón Iglesias, “La masonería, un punto sombrío en la trayectoria de Francisco de Miranda”, trata sobre esta importante figura, quien es con
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br Discussion This observation reports an
2019-04-25
Discussion This observation reports an unusual association of LEMS with LGL leukemia occurring in the same patient, and clearly shows that both diseases benefited from LGL leukemia therapy. Methotrexate and steroids rapidly induced hematological complete remission associated with disappearance of
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The Cochrane review on exercise after lung resection
2019-04-25
The Cochrane review on exercise after lung resection identified three randomized trials involving 178 participants. The meta-analysis found that exercise capacity was statistically greater in the exercise training group compared to the control group following lung resection for NSCLC. No between-gro
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aurora kinase inhibitor br Discussion Unfortunately it was n
2019-04-25
Discussion Unfortunately it was not possible to perfom a RCT comparing medical ozone gas therapy in respect to standard therapy because all our 24 patients had been previously treated with various cycles of antibiotic therapies before we could start the therapy with O3 gas. Moreover the patients
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To date no biomarker analyses of response to
2019-04-25
To date, no biomarker analyses of response to VEGFR targeting agents in breast cancer patients with bone predominant metastatic disease has occurred. Although the bone turnover markers serum c-telopeptide (sCTx), and urinary N-telopeptide (uNTx) were measured at baseline, and uNTX measured every 8 w
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Introduction Pulmonary vein isolation PVI is
2019-04-25
Introduction Pulmonary vein isolation (PVI) is an established strategy of paroxysmal atrial fibrillation (PAF) ablation [1–3]. Radiofrequency catheters have been the standard for AF ablation; however, PVI using balloon-based ablation has been increasingly adopted by electrophysiology laboratories a
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Although Afnan Holmes and colleagues report covers
2019-04-25
Although Afnan-Holmes and colleagues\' report covers substantial ground, several issues remain unexamined. For example, why have facility delivery rates in the country stagnated at roughly 50% over the past decade? Although enhancement of women\'s agency in making health-care decisions is necessary,
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br Signal averaged electrocardiography SAECG
2019-04-24
Signal-averaged electrocardiography (SAECG) SAECG is a high-resolution electrocardiographic technique developed in the 1970s for detecting patients who are prone to SCD after MI. It is based on the theory that lethal ventricular arrhythmias leading to SCD often have a reentrant mechanism. Reentry
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br Study limitations br Conflict of interest br
2019-04-24
Study limitations Conflict of interest Case report Discussion DFT testing is usually recommended to ensure proper functioning of the ICD/CRT-D and verify that there is no acute lead dislodgement [1,2]. For patients with impaired cardiac function, VF induction and shock delivery can cause
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The canonical or catenin dependent Wnt signaling pathway is
2019-04-24
The canonical, or β-catenin dependent, Wnt signaling pathway is critical for the regulation of osteoblast proliferation and survival [95]. Soluble inhibitors of the canonical Wnt pathway such as Dickkopf (DKK1), produced by OBL, and sclerostin, from osteocytes, play important roles in the regulation
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As shown in Fig out of
2019-04-24
As shown in Fig. 2, 40 out of the 60 patients (66.6%) who developed amiodarone-induced hypothyroidism, and 10 out of the 30 patients (33.3%) who developed amiodarone-induced hyperthyroidism, were diagnosed within two years of phosphatidylinositol 4-kinase of amiodarone therapy. Amiodarone-induced h
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br The Medical Education Partnership Initiative
2019-04-24
The Medical Education Partnership Initiative (MEPI) is an innovative and potentially transformative 5-year programme, established by the US Government in 2010, to increase the number of doctors to meet crucial human resource needs in sub-Saharan Africa. MEPI allows African institutions that cgrp a
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Fourth the enormous investment in accessible medicines
2019-04-24
Fourth, the enormous investment in accessible medicines and medical products without investment in checking their quality is profoundly illogical. WHO estimates that only 7% of sub-Saharan countries had a “moderately functioning MRA”. We cannot expect the world\'s medicine supply to improve without
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